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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RTTN All Species: 8.48
Human Site: S1589 Identified Species: 23.33
UniProt: Q86VV8 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VV8 NP_775901.3 2226 248570 S1589 Q G H Q E S T S P R P P H D S
Chimpanzee Pan troglodytes XP_512171 2227 248870 S1590 Q G H Q E S T S P R P P H D S
Rhesus Macaque Macaca mulatta XP_001095442 2227 248978 S1590 Q G H Q E S A S P R P P Q D S
Dog Lupus familis XP_541060 2228 248813 A1591 A Q G P H E T A S A Q L P R D
Cat Felis silvestris
Mouse Mus musculus Q8R4Y8 2226 248470 P1591 Q G Q R E M R P V R P R D S L
Rat Rattus norvegicus NP_001163907 2228 248626 R1592 Q G H L H S V R P V R P R D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506281 1429 157804 A833 Y V D R G G N A L S F M G K G
Chicken Gallus gallus XP_001235279 2232 248669 H1595 N R L M A Q G H S D T T T T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920443 2145 236416 D1516 Q S D T D S S D S A L T Q D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.1 96.5 85.5 N.A. 82.2 82.1 N.A. 42 63.7 N.A. 47.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.7 98.2 91.9 N.A. 89.2 89.5 N.A. 50.9 79.1 N.A. 64.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 6.6 N.A. 33.3 53.3 N.A. 0 0 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 13.3 N.A. 40 53.3 N.A. 13.3 6.6 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 12 0 12 23 0 23 0 0 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 23 0 12 0 0 12 0 12 0 0 12 56 12 % D
% Glu: 0 0 0 0 45 12 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % F
% Gly: 0 56 12 0 12 12 12 0 0 0 0 0 12 0 12 % G
% His: 0 0 45 0 23 0 0 12 0 0 0 0 23 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % K
% Leu: 0 0 12 12 0 0 0 0 12 0 12 12 0 0 12 % L
% Met: 0 0 0 12 0 12 0 0 0 0 0 12 0 0 0 % M
% Asn: 12 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 12 0 0 0 12 45 0 45 45 12 0 0 % P
% Gln: 67 12 12 34 0 12 0 0 0 0 12 0 23 0 0 % Q
% Arg: 0 12 0 23 0 0 12 12 0 45 12 12 12 12 0 % R
% Ser: 0 12 0 0 0 56 12 34 34 12 0 0 0 12 56 % S
% Thr: 0 0 0 12 0 0 34 0 0 0 12 23 12 12 0 % T
% Val: 0 12 0 0 0 0 12 0 12 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _